Which sequence lists the correct order of events in protein synthesis?

• A. DNA in nucleus is unzipped by helicase; Transcription; Translation; Synthesis.
• B. Transcription; DNA in nucleus is unzipped; Translation; Synthesis.
• C. Translation; Transcription; Synthesis; DNA unzips.
• D. DNA unzips; Synthesis; Transcription; Translation.

Answer: (A)

Protein synthesis follows the flow of genetic information from DNA to RNA to protein. First, the DNA in the nucleus unwinds so transcription can occur, producing an mRNA copy. The mRNA then travels to a ribosome in the cytoplasm where translation happens, using the mRNA sequence to assemble amino acids into a polypeptide. The final result is the synthesis of a protein. So starting with DNA unzipping, then transcription, then translation, and finally synthesis matches how the cell really makes proteins. The other sequences misplace steps (translation before transcription, or unzipping after transcription, or placing synthesis before transcription/translation), which isn’t how protein production works.