Which condition describes males born with an extra X chromosome?

Prepare for the PLTW Biomedical Science Test. Study with flashcards and multiple choice questions, each question comes with hints and explanations. Get ready for your exam!

Multiple Choice

Which condition describes males born with an extra X chromosome?

Explanation:
Males born with an extra X chromosome have Klinefelter syndrome, typically with the karyotype 47,XXY. The extra X affects male sexual development and can lead to reduced testosterone, infertility, and sometimes learning or language difficulties. This is distinct from Turner syndrome, which occurs in females with a missing X chromosome (45,X); Down syndrome, which is caused by trisomy 21 (three copies of chromosome 21) and is not sex-linked; and Triple X syndrome, which involves females with an extra X (XXX). So the described condition—males with an extra X chromosome—is Klinefelter syndrome.

Males born with an extra X chromosome have Klinefelter syndrome, typically with the karyotype 47,XXY. The extra X affects male sexual development and can lead to reduced testosterone, infertility, and sometimes learning or language difficulties. This is distinct from Turner syndrome, which occurs in females with a missing X chromosome (45,X); Down syndrome, which is caused by trisomy 21 (three copies of chromosome 21) and is not sex-linked; and Triple X syndrome, which involves females with an extra X (XXX). So the described condition—males with an extra X chromosome—is Klinefelter syndrome.

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