In DNA, the molecule runs in which direction?

Prepare for the PLTW Biomedical Science Test. Study with flashcards and multiple choice questions, each question comes with hints and explanations. Get ready for your exam!

Multiple Choice

In DNA, the molecule runs in which direction?

Explanation:
DNA has directionality along each strand, with nucleotides connected from the 5' end to the 3' end. That means a single strand runs 5' to 3'. In the double helix, the two strands are antiparallel, so one runs 5' to 3' in one direction while the other runs 3' to 5' in the opposite direction. This orientation matters because DNA polymerases add nucleotides to the 3' end, so synthesis proceeds in the 5' to 3' direction on the new strand. The backbone’s negative charge comes from phosphate groups, which is a chemical property, not the direction of the molecule.

DNA has directionality along each strand, with nucleotides connected from the 5' end to the 3' end. That means a single strand runs 5' to 3'. In the double helix, the two strands are antiparallel, so one runs 5' to 3' in one direction while the other runs 3' to 5' in the opposite direction. This orientation matters because DNA polymerases add nucleotides to the 3' end, so synthesis proceeds in the 5' to 3' direction on the new strand. The backbone’s negative charge comes from phosphate groups, which is a chemical property, not the direction of the molecule.

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